Search Results - alexei+degterev

1 Results

Sort By: Published Date Updated Date Title ID Descending Ascending

• Novel small molecule inhibitors of phosphatidylinositol-3,4,5-trisphosphate (PIP3)

  Why is the target important?The PI3 lipid kinase (PI3K) pathway is an important target for anti-cancer drug development because:It’s activated by growth factors, oncogenes (RAS), GPCRs, etc. It regulates an array of critical cellular functions, including survival, proliferation, metabolism and cell motility. PI3K and its downstream effectors are...

  Published: 3/19/2021

  Inventor(s): Alexei Degterev, Benchun Miao, C.v. Ramana

  Keywords(s):  

  Category(s): Diseases: cancer, Therapeutic: small molecule

---