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Cyclic Peptide Structure Prediction via Structural Ensembles Achieved by Molecular Dynamics and Machine Learning (StrEAMM)
Efficient Development of Orally-Bioavailable Cyclic-Peptide Drugs via Molecular Dynamics + Machine Learning
BACKGROUND
Cyclic peptides are a promising drug modality, combining beneficial traits from both small molecules and antibody or protein therapeutics. While many scientists think that cyclic peptides are key to providing orally-available...
Published: 8/7/2023
Inventor(s): Yu-Shan Lin, Jiayuan Miao
Keywords(s):
Category(s): Screening: combinatorial chemistry, Software
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Method and Architecture for Image and Video Signal Measurement and Applications
Measuring color image quality is important for image processing and computer vision tasks, such as remote sensing, medical imaging, consumer application, computer and robotic vision, and handwriting recognition. The most widely recognized method of determining color image quality is the subjective evaluation Mean Opinion Score (MOS), but subjective...
Published: 8/27/2021
Inventor(s): Karen Panetta, Sos Agaian, Chen Gao
Keywords(s):
Category(s): Software
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Abstract from 2012 paper Multiscale image fusion using an adaptive similarity-based sensor weighting scheme and human visual system-inspired contrast measure
SUMMARYTufts researchers have developed a novel image fusion algorithm with superior performance PROBLEMThe goal of image fusion is to combine multiple source images obtained using different capture techniques into a single image to provide an effective contextual enhancement of a scene for human or machine perception. In practice, considerable value...
Published: 7/30/2021
Inventor(s): Karen Panetta, Shahan Nercessian, Sos Agaian
Keywords(s):
Category(s): Software
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Methods and Systems for Multidimensional Sudoku Puzzles, Ciphers, and Generators
BackgroundMany image scrambling and image encryption algorithms have been developed based on different principles. Generally these algorithms can be divided into two categories based on the type of encryption domain SummaryThis invention relates to methods of generating a Sudoku matrix with optimal efficiency without random guesses. The methods comprise...
Published: 1/15/2025
Inventor(s): Joseph Patrick Noonan, Yue Wu, Sos Agaian
Keywords(s):
Category(s): Software, Computer
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System and Methods for Visual Sub-Band Decomposition of Image Signals
SUMMARYTufts University investigators have developed novel methods to enhance, measure, fuse, and process images and videos based on Human Visual System Characteristics (HVSC). Human Visual System (HVS) based image decomposition emulates the way in which human eyes respond to visual stimulus.BACKGROUNDDigital images are subject to a wide variety of...
Published: 7/30/2021
Inventor(s): Karen Panetta, Sos Agaian
Keywords(s):
Category(s): Software
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Algorithm for improved Spatial Sampling Design of DNAPL contaminants
SUMMARYImproved algorithm that reduces sampling required to monitor the remediation of Dense Nonaqueous Phase Liquid (DNAPL) contaminants in subsurface water.BACKGROUNDThe difficulties encountered in the remediation of Dense Nonaqueous Phase Liquid (DNAPL) contaminants in the subsurface have spawned numerous studies relating to evaluation of the benefits...
Published: 1/15/2025
Inventor(s): Linda Abriola, Ke Li
Keywords(s):
Category(s): Software, Cleantech
