Search Results - abraham+sonenshein

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• Inhibitors of Clostridium difficile spore germination and outgrowth

  Inhibitors of Clostridium difficile spore germinationTufts case T001523Technology• Spore formation by Clostridium difficile is a significant obstacle to overcoming hospital-acquired C. difficile-associated disease (CDAD). Spores are resistant to heat, radiation, chemicals, and antibiotics, making a contaminated environment difficult to clean....

  Published: 3/19/2021

  Inventor(s): Abraham Sonenshein, Joseph Sorg

  Keywords(s):  

  Category(s): Diseases: infectious, Screening: target, Therapeutic: antibiotic, Therapeutic: small molecule

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• Spore Vaccine for Rotavirus

  Heat-stable, injection-free vaccine platformThe invention is a novel vaccine platform utilizing the non-pathogenic bacterium Bacillus subtilis as the antigen-producer. A desired antigen can be engineered to be under the control of a pro-vegetative state or a pro-sporulation promoter. Cells are induced to express the desired antigen on the cell surface...

  Published: 7/30/2021

  Inventor(s): John Herrmann, Abraham Sonenshein, Saul Tzipori, Boris Belitsky

  Keywords(s):  

  Category(s): Therapeutic: vaccine

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• Research Tool: Stable reporter system for promoter activity in Listeria monocytogenes

  Stable reporter system for promoter activity in Listeria monocytogenes

  Published: 4/2/2020

  Inventor(s): Abraham Sonenshein, Hyun-Jin Kim

  Keywords(s):  

  Category(s): Research tool: expression system

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