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The invention relates in one aspect to a therapeutic method to treat hemolytic uremic syndrome by administering to an individual a therapeutically effective amount of monoclonal antibody which binds specifically to either Shiga toxin, Shiga like toxin I or Shiga like toxin II. The hemolytic uremic syndrome is typically caused by an Enterohemorrhagic...
Published: 11/25/2022
Inventor(s): Saul Tzipori, Ramaswamy Balakrishnan, Arthur Donohue-Rolfe
Keywords(s):
Category(s): Therapeutic
Heat-stable, injection-free vaccine platformThe invention is a novel vaccine platform utilizing the non-pathogenic bacterium Bacillus subtilis as the antigen-producer. A desired antigen can be engineered to be under the control of a pro-vegetative state or a pro-sporulation promoter. Cells are induced to express the desired antigen on the cell surface...
Published: 7/30/2021
Inventor(s): John Herrmann, Abraham Sonenshein, Saul Tzipori, Boris Belitsky
Category(s): Therapeutic: vaccine
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