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Coherent Hemodynamics Spectroscopy - a non-invasive and real-time diagnostic technology to identify and monitor brain damage
SUMMARYNon-invasive and real-time optical diagnostic technology that offers new way to identify and monitor brain damage resulting from traumatic injury, stroke or vascular dementia. BACKGROUNDCerebrovascular diseases are the second leading cause of death and dementia, and the leading cause of disability worldwide. More accurate measurements of the...
Published: 3/28/2025
Inventor(s): Sergio Fantini
Keywords(s):
Category(s): Medical devices, Diagnostic
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Silk Lamellae Tissue Structures as a Platform for Tissue Engineering
Silk-based transparent films demonstrate excellent biocompatibility and applicability for corneal tissue engineering. Download a detailed description of the invention hereIntellectual PropertyUS Patents 6,140,240; 9,102,916; 9,655,993 and Patents in Japan and several European countries
Published: 6/4/2020
Inventor(s): David Kaplan, Fiorenzo Omenetto, Jeffrey Marchant, Noorjahan Panjwani, Brian Lawrence
Keywords(s):
Category(s): Healthcare, Materials, Medical devices
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Silk Based Microneedle Patches for Transdermal Drug Delivery
Researchers have developed a series of silk-based adhesive materials, including silk-based microneedle arrays, which demonstrate excellent biocompatability and are able to stabilize active biomolecules within the silk matrix prior to administration.Download a detailed description of the invention hereIntellectual PropertyUS Publication 2013-0338632...
Published: 7/27/2022
Inventor(s): David Kaplan, Fiorenzo Omenetto, Konstantinos Tsioris, Eleanor Pritchard
Keywords(s):
Category(s): Materials, Materials: nanoscale, Medical devices
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Processing Methods to Form Porous Matrices from Silk Proteins
Researchers at Tufts University have developed a new porous silk biomaterial which has the mechanical integrity and biocompatibility to be a new bone scaffold for orthopedic applications. Download a detailed description of the invention hereIntellectual Property: US Patents 7,842,780 (November 30, 2010); 8,361,617 (January 29, 2013); 9,132,197 (September...
Published: 4/2/2020
Inventor(s): David Kaplan, Rina Sears, Lorenz Meinel, Gordana Vunjak-Novakovic
Keywords(s):
Category(s): Materials: ceramics, Medical devices
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Silk microspheres and methods for surface lubrication
Download a .pdf version of this invention hereSummaryResearchers at Tufts University have developed an injectable silk biopolymer device to treat joint disease which incorporates the 1,2-Dioleoyl-sn-glycero-3-phosphocholine (DOPC). This new biomaterial consists of silk fibroin microspheres which demonstrate excellent lubrication in friction tests. This...
Published: 8/12/2020
Inventor(s): David Kaplan, Xiaoqin Wang, Vijay John, Noshir Pesika, Rubo Zheng
Keywords(s):
Category(s): Medical devices
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Gold Nanoparticle-Doped Biocompatible Silk Films as a Path to Implantable Thermal-electrically Wireless Powering Devices
Tufts researchers have developed silk-based photothermal devices capable of wirelessly converting light energy into heat. These devices are mechanically robust, implantable, biocompatible and biodegradable, which makes them useful for a wide range of in vivo applications including photothermal therapy, controlled drug delivery, wireless powering of...
Published: 1/15/2025
Inventor(s): Fiorenzo Omenetto, Hu Tao, David Kaplan
Keywords(s):
Category(s): Energy, Materials: polymers, Optics, Medical devices, Therapeutic
