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Water-Based Silk Monoliths
Water-Based Silk MonolithsThe present application relates to amphiphilic polypeptide materials, methods for making and using the same. Provided amphiphilic polypeptide materials are water-based and manufactured using all aqueous processing. Provided materials exhibit a capacity to encapsulate and store biologically active molecules or macromolecules....
Published: 9/10/2020
Inventor(s): Fiorenzo Omenetto, Benedetto Marelli, David Kaplan
Keywords(s):
Category(s): Materials
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Smart Fabrics
SUMMARYResearchers at Tufts University have developed an implantable, conductive nanothread platform capable of making enhanced measurements of multiple physiological parameters simultaneously and continuously, and reporting these measurements wirelessly. BACKGROUNDSmart devices have changed how we interact with every aspect of our lives, including...
Published: 9/30/2020
Inventor(s): Sameer Sonkusale, Rachel Owyeung
Keywords(s):
Category(s): Materials, Diagnostic
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Spectroelectrochemical Total Organic Carbon (TOC) Analyzer
SUMMARYThe use of electrochemical oxidation of carbon with detection of the resultant carbon dioxide gas, is a versatile, easy to use, and cost-effective alternative for accurately determining total organic carbon (TOC) levels in a solution. While a variety of electrodes made of different materials are readily available, they are limited in their capacity...
Published: 12/22/2020
Inventor(s): Samuel Kounaves
Keywords(s):
Category(s): Materials
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Silk Water Lithography
SUMMARYTufts University investigators have developed a room temperature lithography technique that eliminates the need for expensive equipment and minimizes the use of harsh chemicals without sacrificing resolution.DESCRIPTION A resist film that is composed of a biocompatible and biodegradable polymer (derived from silk) combined with a water-based...
Published: 9/30/2020
Inventor(s): Fiorenzo Omenetto, David Kaplan, Miaomiao Yang, Hu Tao, Benedetto Marelli, Sunghwan Kim
Keywords(s):
Category(s): Materials
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Silk Fibroin as a Photoresist in Lithography
Tufts University investigators have developed a lithography resist that eliminates minimizes the use of harsh chemicals without sacrificing resolution. Optical-grade silk fibroin aqueous solution obtained from the cocoons of the Bombyx mori caterpillar is placed on a substrate and spin-coated to form a silk film. Competitive AdvantagesEliminates special...
Published: 9/10/2020
Inventor(s): Fiorenzo Omenetto, David Kaplan, Sunghwan Kim, Benedetto Marelli
Keywords(s):
Category(s): Materials
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Multi-Threshold FinFET Design via Fin Shape Control
Lead Inventor: Soha HassounTufts University Case T001998Overview: Design technique for creating multi-threshold FinFET transistors via fin shape control.Technology: A process for modifying the doping and geometric cross section of three-dimensional transistor fins in order to allow both low-power and high-power transistors on a single integrated circuit.Opportunity:...
Published: 8/17/2021
Inventor(s): Soha Hassoun, Brad Gaynor
Keywords(s):
Category(s): Materials, Semiconductor
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NANOCOMPLEXES FOR DELIVERY OF SAPORIN
Novel protein formulations for cancer therapy using an intracellular delivery formulation.Download a .pdf version of this technology hereIntellectual PropertyUS Publication 2016-0082126
Published: 6/5/2020
Inventor(s): Qiaobing Xu, Ming Wang
Keywords(s):
Category(s): Diseases, Healthcare, Materials
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Chemical modification of proteins and peptides for therapy
A series of stimulus-responsive protein modifications to enhance intracellular protein drug delivery.Download a .pdf version of this invention hereIntellectual PropertyUS Publication 2016-0129120
Published: 4/16/2021
Inventor(s): Qiaobing Xu, Ming Wang
Keywords(s):
Category(s): Healthcare, Materials, Nanotechnology, Therapeutic
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Electrogelation of Silk and Devices for Silk Electrogelation and Delivery
Silk based hydrogels made through electrogelation (e-gels) are excellent biocompatible adhesives. Once formed, these e-gels can be reversible which makes them excellent candidates for on-demand reversible blood clotting devices.Download a detailed description of all of our silk bleeding control technologies hereIntellectual PropertyUS Patents 8,501,172...
Published: 6/4/2020
Inventor(s): David Kaplan, Gary Leisk, Tim Jia-Ching Lo
Keywords(s):
Category(s): Healthcare, Materials, Instrumentation
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Silk Lamellae Tissue Structures as a Platform for Tissue Engineering
Silk-based transparent films demonstrate excellent biocompatibility and applicability for corneal tissue engineering. Download a detailed description of the invention hereIntellectual PropertyUS Patents 6,140,240; 9,102,916; 9,655,993 and Patents in Japan and several European countries
Published: 6/4/2020
Inventor(s): David Kaplan, Fiorenzo Omenetto, Jeffrey Marchant, Noorjahan Panjwani, Brian Lawrence
Keywords(s):
Category(s): Healthcare, Materials, Medical devices
