Search Results - florence+wagner

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• Novel treatment for CTNNB1 syndrome

  SUMMARY Tufts University investigator, Michelle Jacob, and Broad Institute’s Florence Wagner, have shown significant improvements in symptoms of CTNNB1 neurodevelopmental disorder in a heterozygous mouse model using a novel small molecule targeting β-catenin signaling. BACKGROUND The CTNNB1 mutation is an extremely rare genetic neurodevelopmental...

  Published: 4/29/2024

  Inventor(s): Michele Jacob, Jonathan Alexander, Florence Wagner

  Keywords(s):  

  Category(s): Therapeutic, Therapeutic: small molecule

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