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SUMMARY Tufts University investigator, Michelle Jacob, and Broad Institute’s Florence Wagner, have shown significant improvements in symptoms of CTNNB1 neurodevelopmental disorder in a heterozygous mouse model using a novel small molecule targeting β-catenin signaling. BACKGROUND The CTNNB1 mutation is an extremely rare genetic neurodevelopmental...
Published: 4/29/2024
Inventor(s): Michele Jacob, Jonathan Alexander, Florence Wagner
Keywords(s):
Category(s): Therapeutic, Therapeutic: small molecule
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