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SUMMARY Tufts University investigator Nikhil Nair and his team have developed a novel directed evolution workflow to rapidly engineer ammonia lyase (AL) class enzymes for large sequences that are ideal for improving kinetic properties. This technique was used to isolate previously unexplored phenylalanine ammonia lyase (PAL) enzymes with ~2.5-fold...
Published: 8/24/2023
Inventor(s): Nikhil Nair, Karishma Mohan, Vikas Trivedi, Zachary Mays, Todd Chappell
Keywords(s):
Category(s): Therapeutic
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